possible interaction: niacin flushing v. undermethylators

I tried niacin flushing last year, two separate incidents. The first time I developed a bad case of hives. The second time I developed an even worse case of hives, all over my arms, torso, and legs, and it lasted four days.

I suspect there's some interaction between undermethylation and niacin flushing. In particular, I believe I have high histamine levels, possibly caused by undermethylation, and that my histamines were put to use during the niacin flushing.

So if you're an undermethylator, maybe stock up on Benadryl before giving a niacin flush a try. I think that could help.

All just speculation, but there you go.