Antabuse and Sugar Alcohols 
Ab12452
16 y
11,199
† Cross †
Does anyone know if a person on Antabuse can still consume Sugar alcohols, such as Sorbitol and Xylitol. My doctor has been no help with this question.
These are common Sugar substitutes, not drugs. They're often found in sugar-free gum.
Would a person on Antabuse be able to tolerate Sorbitol and Xylitol?
- Re: Antabuse and Sugar Alcohols bnky
15 y
12,408
MoreThis is a reply to # 1,503,364Yes, because although they are called "sugar alcohols", they are metabolised by a different pathway in the liver.
Antabuse blocks Aldehyde dehydrogenase subtype 2 (ALDH2) which is used by the liver to get rid of acetaldehyde. This builds up, and makes you feel sick.
Sugar alcohols are metabolised into glucose through a different pathway, and are not effected by this.
Hope that helps!
- Re: Antabuse and Sugar Alcohols bnky
15 y
12,408
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