People with fibromyalgia do have brain chemistry that is a lot different. They usually do not manufacture enough seratonin or dopamine (neurotransmitters) and don't have enough natural opiate activity.

Many people do get results with Cymbalta wich is an anti depressant that is a reuptake inhibitor of these 2 neurotransmitters. Then for the opiate the drub suboxone is both an opiate and an opiate antagonist, which allows pain relief but blocks enough receptors to keep one fron getting "high" from it.

As far as natural products. There is 5-HTP, DHEA, melatonin and some others. The only problem is oftentimes, instead of converting into the substances you want they will go through a different pathway and form estrogen, testosterone and other things.

The drugs don't agree with everyone, and of course you are adding toxins. But, if they make your quality of life good, then they may be considered as something you take as replacement therapy and make up for the toxins by using diet, exercise, a clean body through cleansing of all pathogens, etc. and still live a long healthy life. A matter of balancing what is important. Of course as a last resort the drugs would be used, as once your on them, they are a lifetime thing, or if not, they can be very difficult to get off of.