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DESSAU: Drug Interactions Of Ivermectin by ICU ..... Morgellons Disease Forum

Date:   1/15/2011 6:08:52 PM ( 7years ago)
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Hi Dessau ~~
Ref:  Albendazole & Ivermectin Protocol ~ Morgellons, Strongyloides, & Filariasis:
This is in response to your PM to me regarding interactions of other drugs taken with Ivermectin.
Drugs with Gamma-Aminobutyric acid (GABA)-Potentiating Activity:  Concurrent therapy with ivermectin & drugs with GABA-potentiating activity (e.g., barbiturates, benzodiazepines, sodium oxybate, & valproic acid) is not recommended.

Benzodiazepines:  Ivermectin may potentiate the activity of benzodiazepines.  Concurrent therapy with ivermectin & benzodiazepines is not recommended.

Inducers or Inhibitors of the p-Glycoprotein Transport System:  Ivermectin appears to be a substrate of the p-glycoprotein transport system; thus, interactions with inhibitors (e.g., amiodarone, carvedilol, clarithromycin, cyclosporine, erythromycin, itraconazole, ketoconazole, quinidine, ritonavir, tamoxifen, & verapamil) or inducers (e.g., amprenavir, clotrimazole, phenothiazines, rifampin, ritonavir, & St. John’s wort) of the p-glycoprotein transporter are theoretically possible.

Alcohol:  Concurrent administration of single doses of ivermectin (150 mcg/kg) & alcohol 4.5% v/v (400 mg/kg average dose) resulted in substantial increases in plasma ivermectin concentrations in healthy individuals, indicating a potential pharmacokinetic interaction. (IMHO, increasing the plasma concentration is a good thing.  You get more drug in the blood to blast the bstrds, more bang for your meds $buck$, & a nice toddy for the body ~~ lol.  That's why I take the vet med Agrimectin cattle pour-on suspension since it's alcohol-based & the tablets, paste, & other types of suspensions aren't.) 

Anticoagulants:  In one patient receiving acenocoumarol (not commercially available in the US), excessive hypocoagulability was reported after occupational contact with insecticide formulations of ivermectin (Epimek, not commercially available in the US) & metidation (Ultracid, not commercially available in the US).  The manufacturer states that no additional case reports of an interaction between ivermectin & oral anticoagulants have been received to date.

(Extract from Medscape Ivermectin Drug Monograph:

Hope this info helps you in your parasite battles!

Cheers ~~ ICU   

My Curezone Posts:

Parasite Drug Protocols:  Roundworms, Tapeworms, Flukes, Filariasis, Morgellons, & Protozoa:


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