And of course "Lyme disease: A Look Beyond Antibiotics" talks about not doing a test until treated for lyme first....
Bb tends to infect the B-lymphocytes and other components of the immune
system which are responsible for creating the antibodies, which are then
measured by an ELISA test or Western Blot test. Since antibody production
is greatly compromised in infected individuals, it makes no sense to use
these tests as the gold standard or benchmark for the presence of Bb (7). We
also are aware that in endemic areas in the US up to 22% of stinging flies
and mosquitoes (2, 8, 9, and 10) are carriers of Bb and co-infections. In
South East Germany and Eastern Europe 12 % of mosquitoes have been
shown to be infected. Also many spiders, flees, lice and other stinging
insects carry spirochetes and co-infections.
Making the history of a tick bite a condition for a physician to be willing to
even consider the possibility of a Bb infection seems cynical and cruel.
To use conventional diagnostic tests such as the Western Blot, one has to
think in paradoxes: the patient has to be treated with an effective treatment
modality first before the patient recovers enough to produce the antibodies,
which then are looked for in the test. A positive Western Blot proves that the
treatment given worked to some degree. A negative Western Blot does not
and cannot prove the absence of the infection.