Hi- I just read about the burning you got and I think it's from the serrapeptase. I got the same thing. Every spot that I have inflammation felt like it was burning the night I took my first dose. I tried it again and it lasted a shorter time. Each time the burning was less. I think it's a detox reaction and probably a good sign. Let me know how you're doing with it if you decide to keep trying the serrapeptase.