Yes. It is possible you will have an outbreak at the start of the cleanse. But unlikely. If you do, it should go away after a day or so. I have never had any Acne outbreaks during a colon cleanse, but I also wouldn't put it out of the equation.
I just noticed from your other posts. If you are wanting a simple cleanse, then your best bets would be Oxypowder , Colpurin or CleanseSmart.... (in that order). These are all reputable colon cleansing products that are simple (dont require you to fast or mix teas/fiber drinks) and the Oxypowder & Colpurin are more effective then the CleanseSmart.
(Just a tip)
Any more questions? because I know this can be VERY confusing for newbies. I would be glad to answer any questions....