5th, Clark states no food or drink after 2pm. I don't know if she meant that to include water or not, but from personal experience, dehydration and flushing toxins don't mix well ... headaches, nausea, feeling like a wrung out dishrag ... or feeling good as the buttpee eases off. Your choice.
People here on post after post encourage flushers to drink all the water they can, just not 20 mins before or after each cocktail.