I have Rheumatoid Arthritis and the symptoms of Lyme are similar - fevers, autoimmune issues, joint pain, etc.
I use CS as an intra-nasal spray about once every 2 weeks. I'm at 6.25 mg of iodine, per day, as Iodoral. I don't opt for the Lugol's, purely out of convenience. I also have gone up to 300mcg of selenium, I forget how much magnesium (shoot me, now), 3000mg Vit. C., Omega-3 (forget how much of that, too), 2400mg Glucosamine, and 1800mg of Chondroitin. I also pull oil in the mornings.
The Iodine therapy has helped to boost my immune system, I believe. I haven't experienced anything with regard to the use of CS and Iodine therapy, YET. I'm keeping a positive attitude about using both without overdoing either.