After 11 days of taking Serrapeptase, I finally stopped; my belly seemed inflamed beyond normal temporary side effects. Each day the pain got worse, and the side effects increased its intensity. This is not my first allergic reaction to supplements; perhaps my body is more sensitive to the substance. I will wait a while, then I will start again slowely, may be up to 30000, but no higher. I have to say that I felt short term improvement for 11 days.