To tell you the truth I felt generally better on it despite the side effects. When I realized I had to stop it I cried. I was started at 5 mg 4X per day of cortisol or hydracortasone. It was explained to me that when you take cortisol, your body makes less, your gland shrinks and you become dependant. Each time you lower your dose, you are creating a state of adrenal insufficiency. The body has to try and make more than it's used to making. I would say that if you have severe provable adrenal insufficiency it would be something to consider. For someone who's borderline or low normal, I would think twice. I would also talk to my doctor about supplementing every other day so that the adrenals don't shrink.