CureZone   Log On   Join
another New England Journal... Article
 

Lugol’s Iodine Free S&H
J.Crow’s® Lugol’s Iodine Solution. Restore lost reserves.



Epsom Salt Encapsulated
Hulda Clark Cleanse Kits



Free Dentist Alternative!
Professional Powder beats Fluoride!



End Constipation Now
Let oxygen remove old, impacted fecal matter as it detoxifies and...


More
More
Serenitii7 Views: 1,095
Published: 18 years ago
Status:       R [Message recommended by a moderator!]
 

another New England Journal... Article


The New England Journal of Medicine Volume 302:1274-1277 June 5, 1980 Number 23

Cholesterol crystals and the formation of cholesterol gallstones

A Sedaghat, and SM Grundy

Abstract

To examine the relation of cholesterol crystallization to the formation of gallstones, gallbladder bile was obtained by means of duodenal intubation in 54 patients (eight with asymptomatic gallstones) and from 17 patients undergoing cholecystectomy for cholelithiasis. Hepatic bile was obtained from nine patients with common-duct stones. Bile samples were examined for cholesterol monohydrate crystals and analyzed to determine the percentage of cholesterol saturation. Intubation in the eight patients with asymptomatic Gallstones revealed a cholesterol saturation of 142 +/- 42 per cent (mean +/- S.D.) and crystals in five patients. Crystals were absent in the other 36 patients with supersaturated bile (cholesterol saturation, 166 +/- 44 per cent) and in the 10 patients with undersaturated bile (cholesterol saturation, 81 +/- 24 per cent). In the 26 patients with symptomatic cholelithiasis or common-duct stones, crystals were not seen in the bile of the seven patients with pigment stones but were present in the bile of all 19 patients with cholesterol stones. (In some cases crystals appeared only after 24 to 48 hours of incubation.) Cholesterol crystallization is probably a prerequisite for the formation of cholesterol gallstones; however, many subjects have no crystallization despite marked supersaturation.


This article has been cited by other articles:


PORTINCASA, P, VAN ERPECUM, K J, VANBERGE-HENEGOUWEN, G P (1997). Cholesterol crystallisation in bile. Gut 41: 138-141 [Full Text]
Eckhardt, E. R. M., van de Heijning, B. J. M., van Erpecum, K. J., Renooij, W., VanBerge-Henegouwen, G. P. (1998). Quantitation of cholesterol-carrying particles in human gallbladder bile. J. Lipid Res. 39: 594-603 [Abstract] [Full Text]

Hope this answers questions.

Cheryl
 

 
Printer-friendly version of this page Email this message to a friend

This Forum message belongs to a larger discussion thread. See the complete thread below. You can reply to this message!


 

Donate to CureZone


CureZone Newsletter is distributed in partnership with https://www.netatlantic.com


Contact Us - Advertise - Stats

Copyright 1999 - 2021  www.curezone.org

0.656 sec, (1)