There is no real good substitute for the bile that your liver produces and your gallbladder stores and squeezes out when your food enters your stomach and small intestine. As long as the bile ducts and the gallbladder are blocked, digestion and metabolism of fat will remain problematic. It would be far more efficient for you to get to the real issue and cleanse the bile ducts than to trying to derive a few short-lived benefits from taking a supplement.