In such extreme cases, there may be as close to 10,000 stones or more in the liver, similar to a fatty liver. So, yes, five cleanses are hardly able to scratch the surface. The full feeling in the liver speaks for itself. There will be a drastic improvement and recovery once the liver is cleansed completely.
It will also be necessary that she aids this process by adjusting her diet/lifestyle according to the needs of her body type (see the Key to Health and Rejuvenation).