I've been on Clarkia for a week and got diarrhea too, on the 5th day and it came immediately after I took it. It lasted for just that day. I am up to 12 drops now. I accidently messed up the drops in the beginning....I started out just increasing the dose 1 drop per day and didn't realize you jump from 4 to 6 to 8 and so on. I haven't really noticed anything too different. I did get some aches and a cramp in my left calf, my head and neck felt tight too for a little but that's about it.