Hi, actually you know what when i use the mouthwash more than 2 times my mouth does feel numb, so what i have been doing is sometimes i use it 2x a day and sometimes If i still feel like my mouth is numb I will use it once a day, but 3 times a day is too much i would say, also if you decide to ingest Grapefruit-Seed-Extract try the tablets, some peopel do say that the Grapefruit-Seed-Extract interanlly can affect you so watch out, but the mouthwash has worked wonders on me, by the way they also sell the toothpaste its the Grapefruit-Seed-Extract dental gel that same website sells it, so maybe instead of using the mouthwash 3x you can use it 2x and use the dental gel, in any case let me know how it goes I am just very excited that we foudn a solutiion!!!