I hope you have found Candex. It works much better than Primal Defense. I found PD very irritating. Its base is iron; iron is known to be an irritant, and if you take it in the dose they say you need, you're getting a lot. Candex does not have "die-off" effect and the Candida doesn't develop an immunity to it. I get it at www.discoveradifference.com. It's also very reasonbly priced. Glad I found this site. :)