Hi, I just started taking MSM myself and I am glad to hear this! I've only been on it for 3 or 4 days. How much do you take per day? I am only taking 1 per day to start with at 1000mg. I haven't really noticed anything other than I am having constipation troubles again. Not sure if it's the MSM though. I did start taking B complex 100mg at the same time but stopped it today because it has yeast and that is exactly what I don't want! Do you or anyone know of a brand of B complex that isn't derived from yeast?