As you know, everyone responds so different to a cleanse. I have done three cleanses and the first one was the shortest and most difficult. For some reason, for my spouse and myself, our first cleanse was the hardest. Actually, the second day was the worst!! A very uncomfortable day. So when we advise friends about the cleanse, we always suggest trying it on a three day weekend or during a time when you can have plenty of undisturbed access to a restroom. The second cleanse was less intense, with less cramping, and the third cleanse was the longest and the easiest to maintain a normal schdule with. Hope that this helps even a little.