They wipe me out too, that's why I can't do them on a Saturday night, I need two days recovery time. I too have gallbladder attacks. But I think that I'm getting dehydrated. I drink tons of water normally, but because of the directions of the flush, I drink less than I normally would. This time I'm planning on drinking tons of water in the morning after the flush, hoping it re-hydrates me. I don't know if that helps, but it's what I'm going to try to resolve the issue.