I know 1 guy who did 50 injections of ozone in 3 months. I could never do it, but I guess the answer would be yes. Here's what he said:
"I did about 50 ozone injections in about 3 months. Before that I
did rectal insufflation for about 9 months. The iv ozone is much
more powerful because you can get more ozone into your system.
It can be difficult finding a vein. You could get swelling if
you use the same vein too much or miss the vein and inject. I
had excellent results using iv ozone and now I have switched to
the ozone steam sauna. I'm having great results with that also
during the past month and a half."