Thank you for your reply! I am taking 1 P&B shake a day in the morning on an empty stomch. So far it has helped to bulk up my stool, but no Mucoid Plaque (MP) yet. My Crohn's Disease has been so bad that I went to see my GI doctor. Towards the end of my appointment, I dropped in a question about impacted fecal matter and MP. Not surprisingly, he was completely skeptical and told me furthermore that the Colonoscopy I had would have revealed any of "that stuff." I didn't have a good response, but also find it hard to believe that my colon would be free of any gunk after a lifetime of eating junk food. He had a good point -- the doctors have given me a colonoscopy -- and I don't recall seeing any "gunk" while they were giving it to me. Any guidance on this matter would be greatly appreciated! Thanks!