I have used proteolytic enzymes and digestive enzymes.
Serapeptase is the enzyme that the silk worm uses to dissolve the cocoon. It is considered the strongest enzyme in the world because silk is one of the toughest natural fibers. Serapeptase has been used in enzyme preparations for humans to dissolve scar tissue, and is also used to prevent the inflammatory response found in arthritis and rhumatiod arthritis, muscle inflammation from overwork or exercise and other debilitating muscle/joint illness such as fibromyalgia.
Not only do raw foods provide enzymes to catalyze the breakdown of that food (part of the life/death cycle) but raw foods also provide enzymes that cause our own digestive systems to manufacture their own digestive enzymes that are naturally produced in the body.
I am a strong proponent of supplementing digestive enzymes when debilitated by digestive ailments of all kinds. Caution is advised for people with ulcers who should not take specific enzymes. Betaine HCL I think is one of them, unfortunately.