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Re: Very important question
dm0923 Views: 33,131
Published: 15 years ago
This is a reply to # 376,768

Re: Very important question

Hi all. I’ve only got a second (back on Sunday), but according to the biopsy report there were, in addition to other things, micro abscesses and a negative PAS. Additionally, some have reported (including myself) that we have some form of granulomas, slightly nodular swelling in our lips. According to from UCSF, “cultures and special stains for acid fast organisms and fungi should be done on all tissue that shows granulomatosis and/or microabscesses.”

According to: from NYU, “A negative periodic acid-Schiff stain on histopathologic examination makes cutaneous fungal infections, such as sporotrichosis or chromoblastomycosis, unlikely.”

So, with a negative PAS, micro-abscesses, and granulomas activity, it would be prudent to perform an acid-fast bacilli test. It might show nothing, but it would be informative and what if it did show something.

MOTT’s are rare; so is our condition.

Agreed, clofazimine is rarely prescribed and has some pretty negative side-effects. Such considerations make it all the more curious that a doc would prescribe it for our condition (I was wrong earlier: the drug also has some anti-inflammatory properties, but the mechanism is still unknown and much more effective anti-inflammatories exist; what would the motivation be for prescribing such a drug?).

Gotta run. Sorry for the hasty post (I’ll update after getting back).

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