I think that this would depend upon YOUR body... I went through a whole Colonix cleanse close to a year ago. Although it worked for me, I was bloated and uncomfortable at times. After the cleanse was over, I did not feel entirely clean.
I should have known better, because in the past I have had discomfort taking things like Metamucil AND one P&B shake was all it took to tell me this was not the ticket for me; talk about uncomfortable!
I waited about a month and then did an Oxypowder cleanse... I had found what worked best for me, the oxygen based cleansers.
I now use Colosan when I do a bowel cleanse... I do not even do the maintenance dose as I have very regular bowel habits now. I chose Colosan over Oxypowder due to the cost. I got six bottles for $100 off of Amazon in early February... I have 4 and a half of the bottles left.
To be fair, if the Oxypowder were more competitively priced, I would be using it as I liked it a little better due to convenience.