One of your problems is you're still thinking of all symptoms as being BAD. No, if they happen after you take something, chances are that's a good thing and means they are WORKING. Study up on the Healing Crisis in the FAQ some more. :)
Livatone Plus should be followed by chinese gentian and milk thistle. That means either chinese bitters or planetary formula's bupleurum liver cleanse or PF's Silmarilyn/Milk Thistle blend. It takes as long and as much herbs as it takes. If you're still getting red eyes you still have a compromised liver/bowel and must keep cleansing both.
Knees don't have any muscle to speak of - but I'm getting technical here. They have bone and cartilage. The muscles are all in the thigh. So does it hurt behind your kneecap or?