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Re: Newfound drug for parasitic infections
 
mattk3 Views: 668
Published: 29 months ago
 
This is a reply to # 2,426,558

Re: Newfound drug for parasitic infections


Tribendimidine is a L-subtype nicotinic AcetylCholine receptor antagonist. This med works on 2 pathways at the same time. Typically Nicotinic and Choline receptors are seperate chemistries.

Stronger (more effective) than Pyrantel or Levamisole, which also are AChE meds. These meds are typically used when traditional Bendazoles do not work, or there is not a trick chemistry that will suppress the parasite. So there are infections where Tribendimidine would be better in the long run, to clear and infection. One needs to know by research of specific species to identify this insight.

These kind of meds, reduce the energy a parasite has, sometimes to zero, for the period of time its concentration is high enough. This typically stops, but does not kill a parasite, like strongyles, but can injure various worms.

There are several filarial species it works on.

Useful for some hook worm species.
https://www.infectiousdiseaseadvisor.com/home/topics/vector-borne-illnesses/safety-of-escalating-doses-of-tribendimidine-in-children-with-hookworm/

Highly effective in treating ankylostomiasis, ascariasis and enterobiasis, these are white worms, that are suppressed by traditional Bendazoles, (white worm meds).

If you search curezone, you will find some things written about the med.

https://www.path.org/media-center/path-clarus-and-the-global-health-investment-fund-announce-an-innovative-25-million-financing-arrangement-to-improve-treatment-of-intestinal-worms-affecting-more-than-1-billion-people-worldwide/


So if a med is designated as the prime med for an infection, it can be used.

Typically an infection is identified, I use the challenge method, where white worm meds, red worm meds, or flat worm meds are dosed for 3 days, to determine which families are present.

If you have a complicated infection, more than a single family, or several species within a family, the enzymes parasites share makes them hard to eliminate.

Infections where worms have spread, travel freely, are either bad species, or the immune system has been lowered to have little effect.

These hyper stage infections can be damaging, and usually need a ramp onto any med that controls the infection, to stop its uncontrolled birth rate.

Suppression of eggs, juveniles, filarial stages, Junior stages, and Adult stages may be possible, and once an infection is identified, several meds in the family (white, red, flat) could be used to suppress the infection.

Once a better picture of the infection complexity is determined, one sets about a plan to go after the most important infections first, and suppress the damage during treatment.

Depending on the situation, it can take months, or years to clear an infection, especially once it has taken hold.

In general, whites travel in the body cavity, mostly sticking to organs, or in safe locations.

In general reds travel where ever they want, circulation, nerve, cognitive are mostly continuous.

Flat worms cause liver distress, digestion and bile issues.

Of course these generalizations do not take into account the mix, extreme level an infection can expand to, or the different pains different stages of a worm can occupy.

You sound kind of complicated.

Generally one starts a routine schedule of dosing.

Safe starter meds are invermectin, albendazole, etc. These can be started on a regular dosing pattern to suppress a lot of infections.

Pyrantel used once can determine if there is an infection inside the GI Intestine.

FenBendazole for three days can be used to identify conventional red worms.

Oxbendazole (half dose) = std dose for humans, 5mg/kg/D for 3 days can be used to identify conventional white worms.

Praziquantel at say 33mg/kg/D for 21 days can be used to identify most flat worm species, where the infection is significant. Have a macrozoom camera ready.

The typical emergency situations, i.e. interventions are filarial hyper infection or stage suppression, GI recapture, and Blood system recapture. (different meds or formulas)

The typical systemic elimination order is flat worms, white worms, red worms. If the liver fails, treatment is useless, flatworms cause rapid loss in detox and liver function, so it is first. White worms generate more toxins due to 2 wall layers, Red worms emit less toxins, cause more damage.

The approach I used, was low dose of many meds, daily, till I figured out what did what.

We know more today.

Emergency situations are vision loss, brain fog, loss of memory, muscle contractions, or difference in control of one area that is not symmetrical with the other side of the body.

Intervention in emergency situations should be done ASAP.

Other than that, it is primarily a systematic evaluation, determination, and then formulation of a plan, strategy, and education on dosing patterns, levels, and how to keep the body in bounds while treatment is performed.

Bacteria, fungal, liver function, kidney function, other systems need supplementation, especially in the early startup stages.

Increase in pulse, blood pressure, can indicate a significant stress on the body, i.e. a significant infection. This can take a few months to get under control, when caught in time.

I spent a year at very high stress on the cardiac and circulation systems, till I learned the ropes.

Education is key.

Action is key.

Communication is key.

There are people that can help.

Don't let this infection get away from you.



 

 
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