high C dose of pure vitamin C makes the blood very acidic and so the body pulls out minerals from the bones to balance it. You can get "hollow teeth" from this. and osteoporosis. I use high dose vit C to clear out my arteries but only do it once or twice a week and after 3 or 4 hours I down 4 calcium/magnesium pills. But it has done wonders for my circulatory health.