When taken orally Prazi goes through a chemical change in the liver before being released in the bile. Taking it in an enema would not change the result if your liver is not releasing bile. I imagine it would hurt like hell.
There are lots of methods to get bile to flow. Liver flush, coffee enemas, organic apple juice with taurine. I found Solgar Liver Complex on a daily basis keeps my bile flowing. I don't sell it and am rather disgusted about the cost but it has been the answer for me.
It is actually more important to get and keep the bile flowing than it is to get the Prazi in.