Olive oil and grapefruit juice can hardly be classified as drugs or as supplements.
It is just food.
Plain fruit juice.
Fruit of olive and fruit of grapefruits.
Nothing else added to it.
Call it a larger portion of salad dressing, and it will sound more like a food, less like medicine or a supplement.
Yes, there are many Liver Flush recipes out there that ask for more than just olive oil and juice, but unless you are suffering from gallstone attacks, or from some serious disease like cancer or AIDS, drinking just plain fresh fruit juice and Extra-Virgin Olive-Oil will do as much good as an other much more complicated Liver Flush recipe ...
So, no need for supplements or other remedies ... just start drinking oil.
Take just 2 spoons of oil with some juice every morning and it will give you some health benefit after a few weeks or months.