Well, some people call the megadosing of vitamin C that Pauling recommended "crazy", but it was based on scientific principles: he looked at the amount of C that animals synthesised, worked out the amount per kg of body weight, scaled it up to human weight and then it needs to be adjusted for actual body weight and in his case, this worked out to about 18 grams per days, which sounds "crazy" to people used to dosing in milligrams.
He also said the body needs more when suffering stress or actual disease.
I believe the "Iodine Doctors" only recommend 50mg per day in order to achieve saturation, and when it is believed saturation has been achieved then cut back to 13.5mg per day. I'm not sure what is their take on doses higher than 50mg.
Trapper recommends doses much higher, I believe to get over detox side-effects. I don't know on what basis this has been determined: presumably his own experience and that of others. Well a lot of "official" medicine is actually quite empirically-based (more than we sometimes realise), so trapper's approach isn't quite so "unmedical" as some may accuse him of.
Nevertheless, I can understand why some people might be more cautious.
For myself, I've only recently started and will stick at around 50mg per day for the time being, and see how it goes. I'm in the UK which people seem to think is less "halogenated" than the USA. I'm not actually sure about that. Some of us live in areas where the water is fluoridated, although I don't, fortunately.
I'd think we have as much bromine in our furnishings etc as the USA. Bromine salts in bread were supposedly banned here in the 1990s, but things have a way of creeping back in, especially when you have governments like ours that are keen on "deregulation". (I don't eat bread myself but my wife does and I worry on her account. Also about the PUFA that's probably in it as well).
And of course we have chlorine in the tapwater and in swimming pools. Wouldn't it be great if both of those were iodized instead?
BTW, I think all of the "Iodine Doctors" say we should actually be taking Iodine under the supervision of an "iodine-literate doctor". How's that going for most people? I doubt if there is an iodine-literate doctor in the whole of the UK, and if there was, I would not know how to find one. There might have been once, but they are long-retired or in the graveyard.