I had a hole in my neck that looked very much like the one on your leg and it filled in completely all by itself. It took about 8 weeks for the wound to heal completely. I now have a pretty ugly scar, but it looks a whole better than some of the skin grafts I have seen on people's noses. I poured hydrogen peroxide in the wound and scrubbed the edges hard with a Q tip dipped in hydrogen peroxide twice daily. Then I filled the hole with a mixture of goldenseal and turmeric. Then I coated the edges with vassoline and covered it.