When you say secondary AI/AF are you talking the more wired/tired or the completely fatigued AF.
I have more of the wired (hardly if ever tired but when I am...my body will not shut down).
At this point cortisol suppression would be a very welcome relief for me!!!
Pregnenolone worked great when I felt more tired but at this point I need something to slow me down. I was doing progesterone but either the dosage was not high enough (stimulated estrogen) or was converting to cortisol.