Some stones are too big to come out, at least in my case. I have a stone now for 15 years and have done 100 flushes. I stopped flushing around that time. A few times a year my gallbladder reacts and I drink 1 tbs Epsom Salts (=magnesium sulfate)in warm water and the pain goes away in 20 minutes. In May I had a different pain and decided to do another ultra sound. My stone was measured at 2.6 cm and I had no inflammation and the gallbladder wall was not thickened. So the MD suggested, since I have had it for 15 years, to leave it alone.