I assumed that would be the case too which is why I bought Mesosilver and later Utopia by the gallon (which I got better results from than the Meso).
But for direct application I find the homemade works noticeably better. Putting in the nose ears gargling etc for flu bronchitis etc, or pink eye, ear infections, sore throat etc.
Maybe drinking it works better with the commercial that's more colloidal would be intuitive but I haven't really been able to confirm it.
This surprises me and seems counterintuitive to say the least, but it's what I've experienced. And I have a fairly large sample size since I use it at my school for employees, students, etc plus my family where I have to kids with Crohns disease etc.
OTOH I use CS and DMSO to kill the Crohns intenstinal flare ups. One of my sons claims the commercial works better for that.