Deficiency symptoms include anemia, bone disorders, defective spinal cord, hair greying and hair becoming fine and straight, losing its curl, infertility; weak connective tissue as evidenced by heart problems such as enlarged heart, weak aorta with holes and ruptures, aneurisms, varicose veins, wrinkling skin, and hernias. Copper deficiency greatly increases the lipid peroxidation of lipoproteins and cardiovascular tissue. It causes high cholesterol levels, and heart attack victims have low copper levels in the heart.