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Re: Cellulase ok??
 
dvjorge Views: 3,061
Published: 5 years ago
 
This is a reply to # 2,187,382

Re: Cellulase ok??


I am not sure if that may be the case of polymicrobial biofilms or bacterial biofilms. On the other hand, candida albicans biofilms aren't affected by cellulase or hemicellulase, to my knowledge.

Here you can see the compostion of candida albicans biofilm matrix and candida tropicalis matrix. As you will see, cellulose isn't mentioned. Glucose is the biggest part of the matrix.

See this fragment:
Biofilm matrix of Candida albicans and Candida tropicalis: chemical composition and role in drug resistance.
Al-Fattani MA1, Douglas LJ.
Author information
Abstract
Matrix material was extracted from biofilms of Candida albicans and Candida tropicalis and analysed chemically. Both preparations contained carbohydrate, protein, hexosamine, phosphorus and uronic acid. However, the major component in C. albicans matrix was glucose (32%), whereas in C. tropicalis matrix it was hexosamine (27%). Biofilms of C. albicans were more easily detached from plastic surfaces by treatment with the enzyme lyticase (beta-1,3-glucanase) than were those of C. tropicalis. Biofilms of C. albicans were also partially detached by treatment with proteinase K, chitinase, DNase I, or beta-N-acetylglucosaminidase, whereas C. tropicalis biofilms were only affected by lipase type VII or chitinase.

Chitinase and Glucanase degrade the biofilms.

I see no reason of buying Candex or cellulase enzyme when you can get Interfase that contain chitinase and glucanase. These are the TWO more important enzymes in my opinion.

Jorge
 

 
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