Hi I think if feeling cautious seperate could be one way to go. I think ICU says taken together has higher cure rate but it seems like it would probably be stronger on the body though. It could go by individual case though but I feel cautious about taking medication with parasites so I tend to seperate them. This week I did albendazole for five days and now praziquantel for 1-2 days. It is possible too that prazi mixed could release some stuff faster too so who knows, it could go ether way.