Hi there & thanks. I've heard that it isn't good to chelate if bile isn't flowing, like mine isn't. That the chelator will just move metals around the body because they cant be eliminated by the detox channels (my detox pathways are basically not working). I've heard from many that tried to chelate with very poor detox pathways and they just got worse. I am so on the edge I can't afford at all to get any worse. If you check my message I take methylators - Sam-e & DMG in tiny doses, and then B12 injections. They keep me alive too, but I can barely tolerate crumbs of them any more. Methylfolate makes me REALLY irritable.