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triclabendazole resistance
 
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Published: 12 y
 

triclabendazole resistance


Hi, I was able to get the triclabendazole and I ordered 4 boxes of it. Well, it doesn't seem to be having the effect that it did the first time I took it in france. About a month ago.

So, just I think if people know they have the fasciola infection it may be pretty wise to do atleast the 10mg/kg dose and do another one 12 hours later.

My first reaction to the egaten was wonderful. Within 5 minutes large colonies dislodged from thier sites. And they were stunned for nearly 5 days. Except they eventually came back to life and I believe built a resistance to the medicine.

Also another extremely strange thing, I used a car battery to zap some of them about 10 days ago. This worked well initially but when I went back to try and treat them they are simply non responsive. Even to high amperage settings. So, these creatures do have a way of morphing and adapting.

I spent most of yesterday trying to find out what to use for resistance flukes. The only thing I could find was a study that said ivermectin allowed the fluke to absorb more triclabendazole into thier skins. On the same token ivermectin did nothing to reduce the laying of eggs or damage them in any way.

That is the only article I have come across that tries to alter the flukes resistance somehow, and i feel it is questionable considering some of the other articles I have read about it.

Who knows if the car battery incident causes them to change and morph into a state where the triclabendazole isn't absorbed as well.

Compound alpha worked really well at damaging their reproductive organs from one of the article.

I don't know. Just really lost right now as to what to do.
Any one got any ideas about resistant flukes?
David

 

 
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