the best is to space them throughout the day. its the elemental that works on the cysts and elemental Iodine is gone from the bloodstream in two hours. you need at least 50mg but 100mg is better. be done with all of them by 6 in the evening to avoid possible insomnia.
something like 2 at 8AM, 10, 2PM and 4. that would work really well.
200mcg of selenomethionine and 9mg of boron. salt and vit C as needed. that should get you started.
read the recommended posts by clicking on BSA, RN, etc. lots of reading to do.