as to dosage, my 50ml bottle clearly states 10 drops daily, of course after taking Ionic Copper solidly for a full month or more, reducing to 5 drops or even taking this supplemenet every few days would ensure one has sufficient copper.
and as to seeing evidence this is not plausable with those parasites that have resided within the sub-cut tissue or internal organs as if it were the case in intestinal/colon areas.
die-off is not always pronounced, I have felt periodic extreme fatigue for years, and since taking the Ionic Copper, feeling juck with a sick looking pallor. Any itching I felt was more likely to be my immune reaction to their activity and toxins but I really don't think skin itching is always significant to mean die-off, over the years I had plenty red flaring itching streaks whilst taking medication but still had repeated cycles of continuing activity year later, by this I mean disseminated and not intestional infestation.
Copper is known to stimulate collagen production, it is included in some beauty creams but nothing beats taking this element internally when it is known there can be deficiencies as in food natural or otherwise.