Excess bile or bile that is not properly nuetralized/converted might further aggravate leaky gut/lining of the gut.
Some good links on SIBO:
Interesting that SIBO might cause bile acid conversion/malabsorption problems leading to more diarreah and possiblly more GI irritation :
A good question is that some bad bacteria strains might be resistant / utilize bile salts:
I know Tony Orlando took dews bile salts and he said it helped him but everyones gut ecology might be slightly different. He might have had the necessary good bacteria for bile conversion. I stopped doing them because they were aggravating my gut too much. Ive had to supplement with some sodium bicarbonate/potassium bicarbonate to help nuetralize some of the excess/ improperly converted bile. Although i dont like getting in the habit of the bicarbonates cause they can be a little hard on the kidneys. I remember reading somewhere that some of our flora helps to convert bile into a less harmful substance? So the lack of certain good flora might cause bile conversion issues.