I was wondering if anyone has had any side effects of getting brain fog and fatigue from MSM. I am not sure if it is MSM that gives me a brain fog. I am also taking grapeseed extract other than MSM. So, I am thinking it is either one of them. I started off with just 500 mg and then raised it to 1000 mg yesterday. I am tired and have a weird brain fog today where I am unable to concentrate. I also have dark circles under my eyes when I wake up...even after 8-9 hours of sleep. I take MSM for skin and hair benefits, which it does help with. Just curious if anyone else also noticed such effects from MSM ?