I had the experience of a goiter for a couple of years, that wouldn't go down no matter how much I detoxed and how little or how much iodine I took. I kept reading goiter was because my thyroid wasn't getting enough iodine, or that I needed iron. I was very disappointed finally to realize I had a tired thyroid that just wasn't going to go no matter how I urged it. My goiter went away when I took enough thyroid hormone to reduce my TSH.
Not to say this is you. Just to give you an endpoint so that if this becomes your reality, you didn't fail, and you did wonderful things for your health along the way.