I guess that bitters don't work for everyone. They don't seem to work for me. It isn't "one size fits all", as the sellers of these herbs imply. I still have some stones to get rid of but I think they may be enormous. In any case, I am amazed that coffee doesn't make me feel bad any more. All in all, I don't understand what makes our livers tick; it seems to be one step forward and one (or two) steps back.