I used to use Eclectic Institute, but Milk Thistle always made me feel a lot worse. It always caused hypoglycemic symptoms.
The first (and worst) panic attack I ever had was because I was just beginning to realize the damage I was doing. I drank like usual, but decided to take Milk Thistle to try and block out some of the damage I was doing. I also smoked some good weed that night and had the most massive panic attack ever. I hallucinated that I was dieing. So scary.
I couldn't be around weed again for a long time because the smell would set off panic attacks every time. This was before I had ever experienced hypoglycemia. Similar to hypoglycemia, but in hypoglycemia there is innate knowledge that you need to eat. It's weird.