You might not feel different. It doesn't really matter. MSM stimulates glutathione and everyone needs glutathione. In fact, we are supposed to get biological sulfur with every meal we eat but that is a thing of the past, unless you drink raw milk or eat your veggies right from the garden, just wipe the carrot off on your pants and dig in!
Like I said, it took a year before I noticed some of my fixes. I had stopped taking it but now I'm back.