I just e-mailed with a poster from a lyme forum and she told me that taking Iodine had increased her number of nodules. She could have hashi's, didn't say, except that she had an auto-immune disease. I don't know what to reply. She is convinced that she can't take iodine. Since I believe Iodine deficiency is the root of the problem, I would experiment with different combinations, topical vs. oral, SSKI before iodine, etc. I also e-mailed with someone who has connective tissue disorder and she says Iodine causes thyroid problems. I sent her info but who knows if she will believe it. It is frustrating to watch people be influenced by misinformation.