Re: A note about probiotics coming back

Hi Cheshire. Yes, I am still around. It seems that HPI may not always work first time around, though many folks do report success from one round. For others it may take several courses. There is probably a lot of variation in beneficial bacterial communties from one donor to another. And of course there is the notion of "competitive exclusion" whereby the recipients microbiota attempts to out compete the donated bacteria for receptor sites. The Human colon is a competive arena where bacteria are constantly in a state of flux. However, there is a certain degree of homeostasis within the microbiome. I suppose you could say it is a classic example of Darwin's principal "survival of the fittest". This is precisely why manufactured probiotics don't implant; the are are out competed by hardier and more numeros bacterial strains Tweet